| Idea Name: |
CANCER CURE |
| Slogan: |
GREEN TREATMENT FOR CANCER |
| Supervisor Name: |
Dr Yasmin Badshah |
| Supervisor Designation: |
Assistant Professor |
| Supervisor School: |
ASAB |
| Supervisor Department: |
HEALTHCARE BIOTECHNOLOGY |
| Contact number: |
03315216550 |
| Email ID: |
[email protected] |
| Abstract: |
| It is predicted that this chloroplast-targeted transient expression technique could feasibly generate a cervical cancer vaccine based on HPV16 that could be efficacious for low-income countries. Plant viral vectors have been utilized to produce HPV vaccines. The methods optimized to express VLPs based on HPV16 L1 protein using the TMV-deconstructed vector MagnICON expression from Tobacco plants. |
| What is the unmet need in society that your idea will fulfill ? |
| Plants can be used as inexpensive and facile production platforms for vaccines and other biopharmaceuticals to combat diseases like Cancer. |
| Who needs it ? How many would benefit ? |
| People of developing countries cannot afford cost for treatment for such diseases. Such treatment would be more benefiting for cancer patients. Moreover, Plant based vaccines has less side effects for human health. |
| How will the solution works |
| Pentameric capsomers, like VLPs, are highly immunogenic. L1 expressed in transplastomic lines retained their immunogenic properties, as determined by antigen capture ELISA, and plants expressing GST-L1 appeared identical to wild-type plants in both morphology and fertility. Use of the structural proteins L1 and L2 to generate vaccines based on VLPs, plant-based immunotherapies have also been pursued for patients who are persistently infected with HPV. |
| Who are your competitors ? How is your solution different |
| Attractive features such as lower production costs, fewer purification steps, and high levels of safety and efficacy make plant-derived pharmaceuticals a platform technology that suits the needs of developing world markets. It is hoped that for resource-poor nations. |
| Status: |
new |
| Entry Date & Time: |
2022-12-15 (0817) |
