Idea - FICS

Oncus

Team and Contact Details

Student Name School Degree Year Email
Maha FatimaASABUndergraduateFourthmaha.khan127@yahoo.com
Iqra MajokaASABUndergraduateFourthiqramajoka98@gmail.com
Huda MunawarASABUndergraduateFourthhudaqureshi@hotmail.com

Inter School Idea ? No
Do you need expertises from another area: No
If Yes please provide details of expertises you need:

Idea Details

Idea Name: Oncus
Slogan: Arming HSV to Erase Cancer
Supervisor Name: Yasmeen Badshah
Supervisor Designation: Associate Professor
Supervisor School: ASAB
Supervisor Department: Atta-ur-Rahman School of Applied Biosciences
Contact number: 051-90856145
Email ID: yasmeenb@asab.nust.edu.pk
Abstract:
    Human papillomavirus infection leads to the development of cervical cancer in women. Our aim is to target and kill cervical cancer cells by using herpes simplex virus, an oncolytic virus.
What is the unmet need in society that your idea will fulfill ?
    Due to societal taboo, cervical cancer is usually ignored. Cases of misdiagnosis and late diagnosis are frequently reported. Hence, the treatment options are not very effective. With this therapy, cervical cancer can be treated and the patient would have a chance to live a normal, painless life.
Who needs it ? How many would benefit ?
   50% of young women get infected with HPV. By the time cervical cancer is correctly diagnosed, it has already progressed to an advanced stage. With the therapy we
How will the solution works
    Herpes Simplex Virus (HSV) is known to exhibit oncolytic behavioural. We propose the use of a third-generation HSV to kill the cervical cancer cells. The HSV virus will be engineered to remove its pathogenic genes. The in vitro efficacy of recombinant HSV on human cervical cancer cell lines will be evaluated.
Who are your competitors ? How is your solution different
    Our competitors are pharmaceutical companies who are working on immunotherapies for cancer. The solution we provide is innovative because we are using HSV as a tool to kill cervical cancer. Not many people are working on this in Pakistan yet.
Status: new
Entry Date & Time: 2021-01-14 (1613)