Idea - FICS

Team VAXEOGEN

Team and Contact Details

Student Name School Degree Year Email
Azka YaminASABUndergraduateFourthazkachaudhry9951@gmail.com
Mahnoor QureshiASABUndergraduateFourthmahnoorq15@gmail.com
Maryam ZahraASABUndergraduateFourthmzahra.bsabs10asab@student.nust.edu.pk

Inter School Idea ? No
Do you need expertises from another area: No
If Yes please provide details of expertises you need:

Idea Details

Idea Name: Team VAXEOGEN
Slogan: VACCines against Evolving pathoGENs
Supervisor Name: Dr. Amjad Ali
Supervisor Designation: Assistant Professor
Supervisor School: ASAB
Supervisor Department: Atta-ur-Rahman School of Applied Biosciences (ASAB)
Contact number: +92 333 9191903
Email ID: amjad.ali@asab.nust.edu.pk
Abstract:
    Acinetobacter baumannii is a bacterial pathogen that causes nosocomial infections; notorious for its growing resistance. We will predict vaccine candidates within its genome using reverse vaccinology.
What is the unmet need in society that your idea will fulfill ?
    A. baumannii is among the critical priority group in WHO’s list of escape pathogens. As previous treatment options are failing; a vaccine against these will prevent high risk groups from being infected and will save enormous sums of money and healthcare resources.
Who needs it ? How many would benefit ?
   People undergoing programmed or emergent surgical procedures or requiring ICU will need it during treatment; also, others that are at risk of acquiring skin infection from injury etc. eg. military personnel. A study in 75 different countries found that A. baumannii was the 5th most common pathogen.
How will the solution works
    The project will lead to the identification of potential vaccine candidates, and specifically epitopes within them that are non-allergenic, and highly immunogenic. Linked together with a potent adjuvant via linkers chimeric vaccine will be designed. This design will further be expressed in wet lab studies. This multi-epitope vaccine, once completely prepared and administered, will work as a prophylactic vaccine which will stimulate both humoral and cellular immunity in the patient.
Who are your competitors ? How is your solution different
    Our vaccine candidates predicted through reverse vaccinology will compete all other researches of experimentally found potential vaccine candidates. This technique reduced the overall cost & time for research exponentially. Our research is also the most updated one with the most recent found strains
Status: new
Entry Date & Time: 2020-12-20 (0855)