Idea Name: |
Formulation development |
Slogan: |
DEVELOPMENT OF THERMOSENSITIVE SOLGEL FOR INTRNASAL DELIVERY OF LAURIC ACID |
Supervisor Name: |
Dr. M Zaman |
Supervisor Designation: |
Associate professor |
Supervisor School: |
SEECS |
Supervisor Department: |
Pharmacy |
Contact number: |
+92 333 6823913 |
Email ID: |
[email protected] |
Abstract: |
Thermosensitive solgel is prepared loaded with lauric acid deliver via intranasal route to target brain to treat epilepsy. Insitugel is sol at room temperature and turn into gel when come in contact with nasal mucosa sustain the drug release and enhance the bioavailability of drug and by passing the first pass effect. Poloxamer 407 has excellent thermo-sensitive gelling properties used in solgel. |
What is the unmet need in society that your idea will fulfill ? |
It is a novel approach for drug delivery to target brain enhance bioavailability and hence therapeutic efficacy. It is effective for unconscious and geriatric patients also. The cost-effective product with better therapeutic outcome. |
Who needs it ? How many would benefit ? |
Product is easy to manufacture, without using any high-tech equipment. The local manufacturer can easily take up this formulation to process in their industries. Epilepsy is amongst the most common serious neurological conditions., the formulation can be beneficial for a large pole of population. |
How will the solution works |
The current project is the solution of drug and product related issues, such as solubility, bioavailability, therapeutic efficiency, and patient compliance. Thermosensitive solgel based nasal spray is the solution of bioavailability as measured dose of drug administered in the nasal cavity through meter dose nasal pumps. Sustained release is also achieved. Noninvasive approach and hence improvement in the patient compliance. lauric acid is fatty acid better permeate when deliver intranasally. |
Who are your competitors ? How is your solution different |
The competitors of the products may be not considerable, as no such product is available in the market. Drug available in the market in the form of tablet, but cost effectiveness and ease in administration would make it more suitable for the manufacturer as well as for the patient. slot pulsa tanpa potongan 2023 |
Status: |
new |
Entry Date & Time: |
2022-12-31 (1355) |