| Idea Name: |
Product Development |
| Slogan: |
Patient compliance with better therapeutic outcomes |
| Supervisor Name: |
Muhammad Zaman |
| Supervisor Designation: |
Associate Professor |
| Supervisor School: |
Other |
| Supervisor Department: |
Department of Pharmaceutical Sciences |
| Contact number: |
03336823913 |
| Email ID: |
[email protected] |
| Abstract: |
| Depression is a global disorder that is affecting worldwide. For the treatment of this disease, various medicines are available. Hypericin is a natural substance that can be utilized for treatment of depression. The current project aimed to prepare nano-emulsion of Hypericin that can be delivered through the intranasal route and then will be evaluated in-vitro, ex-vivo and in-vivo. |
| What is the unmet need in society that your idea will fulfill ? |
| The current available dosage form of various anti-depressants is not specific for many unconscious patients. The poor bioavailability of the drug when provided orally is also a cause of making a novel formulation of this drug, i.e., nano-emulsion. |
| Who needs it ? How many would benefit ? |
| Depression conditions are increasing day by day and affects 121 million people and is among the leading causes of disability worldwide. So, this formulation can be beneficial for a large pool of the patients in Pakistan and in other countries as well. |
| How will the solution works |
| The current project resolves many products related issues of anti-depressants; such as solubility of drug, bioavailability, therapeutic efficiency, and patient compliance. Ethanol and beta cyclodextrin based nano-emulsion is the solution of solubility of drug and also decreases the permeability problems. The measured dose of drug administered via intranasal route would be the solution of bioavailability issues and hence improvement in the therapeutic efficiency and patient compliance. |
| Who are your competitors ? How is your solution different |
| This drug is not synthesized in Pakistan and thus it can be a very productive product when available in market. Dose of Hypericin is low and also will have an added benefit of cost effectiveness and ease in administration would make it more suitable for the manufacturer as well as for patient. slot pulsa tanpa potongan |
| Status: |
new |
| Entry Date & Time: |
2022-12-30 (1842) |
